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JEFFREY LAURENCE, MD
Translational Research
Division of Hematology-Oncology
Weill Cornell Medical College
Laboratory for AIDS Virus Research
at New York Blood Center
310 East 67th Street, 2-14B
New York, NY 10021
AUTHOR
GUIDELINES
Editorial Scope and Policy
Translational Research publishes original investigations in the
broad
fields of laboratory and clinical medicine. It aims to expedite
the translation of scientific discovery into new or improved
standards
of care by promoting a wide-ranging exchange between
basic, preclinical, clinical, epidemiologic, and health outcomes
research. Reports
of purely laboratory or animal investigations
should have the potential for application to human disease, and
reports of preliminary
human investigations should have the potential
for advancing our understanding of the biology of human
disease. Reports of public health
research should have the potential
for application to the clinic, disease prevention, or healthcare
policy. Case reports/series are encouraged,
especially if they provide important mechanistic insight or illuminate a novel therapeutic principle.
Review manuscripts are welcomed
for both state-of-the-art comprehensive
reviews, directed at research scientists in specific
fields, and more general informative reviews,
directed at the
broader community of clinical investigators. Originality is critical
in order to contribute to the medical literature,
and the perspective
should be fresh and the synthesis unique. Authors of reviews
should realize that the Journal is multidisciplinary
and that review
articles for such a journal require appropriate interpretive material.
Clarity of presentation is a major criterion for
acceptance.
Scientific commentary about published articles may be submitted
as a Letter to the Editor. These comments should be directed
at
confirming the results (from a different approach), extending the
original report, or refuting results or the authors' interpretation.
Reports describing preliminary findings that offer hypothesis-generating insight into recognized problems may also be submitted as a
Letters to the Editor. Maximum length is 1000 words; maximum number of references is 15. The Editor reserves the right to decide on
publication
of letters, shorten them, remove objectionable comments,
and make other changes in accord with the style of Translational Research.
Original research of limited scope may be submitted as a Brief Report, and should contain concise accounts of the purpose of the study,
methods used, results, and discussion. Maximum length is 1500 words; maximum number of references is 15.
Papers reporting studies
in human subjects must be accompanied
by statements that the research was carried out according to the
principles of the Declaration
of Helsinki, that informed consent
was obtained, and that the author's institutional review board has
approved the study. This statement
must be included in the
Methods section. The Journal encourages authors to discuss the
ethical concerns in research that involves significant
risk to participants.
All clinical trials that prospectively assign human subjects to intervention and comparison groups for the purposes
of evaluating the cause-and-effect relationship between a medical intervention and a health outcome must be registered with a public
registry before submission of a paper based on the trial. Studies that are designed for other purposes (retrospective records review,
pharmacokinetics studies or assessment of major toxicity) are exempt from the requirement. Trial registry name, registration identification
number, and the URL for the registry should be included in the Acknowlegements. Examples of registries are the US National Library of
Medicine registry ( http://www.clinicaltrials.gov) and the International Standard Randomised Controlled Trial Number (ISRCTN)
registry ( http://www.controlled-trials.com).
The publisher and editors of Translational Research subscribe
to
the definitions of authorship as set forth in the Uniform Requirements
for Manuscripts Submitted to Biomedical Journals; accordingly,
we expect each listed author to accept full responsibility for
the paper. Manuscripts submitted to Translational Research are
reviewed (and ultimately published) with the understanding that
all potential copyright conflicts have been addressed by the author(s)
and that all overlap with other publications by the
authors or by others have been disclosed. Moreover, in the
event that fraud or
other irregularity is alleged within 5 years of
the appearance of a paper in Translational Research, it is our
expectation that
the authors will at our request produce both the
actual data on which the paper was based and documentation of
adequate resources to
have carried out the work in question.
It is understood that statements and opinions expressed in articles
and communications are those
of the author(s) and not necessarily
those of the editor(s) or publisher, and the editor(s) and publisher
disclaim any responsibility
or liability for such material. If the
manuscript receives favorable consideration, a form transferring
copyright and confirming authorship
will be sent to the corresponding
author. It must be signed by all authors. If US Government
jurisdiction precludes copyright transfer,
provide a specific
statement of exemption.
Review and selection
All articles are evaluated by the Editor for suitability
for consideration
for publication in Translational Research. Potentially
acceptable submissions will also be reviewed in detail
by two
additional referees with expertise in the specific area. All revised manuscripts are carefully re-examined with no guarantee of
acceptance, and authors will only have two opportunities to make revisions to the same manuscript. Final acceptance
is based on originality,
significance, documentation of conclusions,
and form of presentation.
Early Online Publication
Accepted articles will be
published online ahead of the printed issue and can be viewed at http://translationalres.com/inpress. Early online publication
significantly reduces the time from acceptance to publication to approximately 4 weeks.
Manuscript preparation and organization
Manuscripts should be submitted online at http://ees.elsevier.com/transres . The website guides authors stepwise through
the submission
process. Submission items include a cover letter (save as
a separate file for upload), the manuscript (including title
page,
abstract, main text, references, and figure legends), tables, and
figures. Revised manuscripts should also be accompanied by a
separate file (separate from the cover letter) with responses to
reviewers' comments. Do not import figures or tables into the text
of the article. Original source files (not PDF files) are required
for online submission. Files should be labeled with appropriate
and
descriptive file names (e.g., SmithText.doc, Fig1.tiff,
Table3.doc). The manuscript must be written in English and typed
double-spaced.
Please send queries concerning the submission or review process
to the Managing Editor, Michael Franklin, at frank061@umn.edu.
The main sections of all manuscripts should be indicated with
capitalized head set flush with the left margin. The organization of
review articles should be appropriate to the content of the review.
The following organization is expected for manuscripts describing
original investigations.
Title page. Include affiliations of the author(s). Also indicate the address of the author to whom
correspondence and reprint requests should be directed; include business and fax numbers.
Abstract. An abstract of 250 words
or less should orient the
reader to the problem, describe the major observations, and state
the principal conclusions, all in one paragraph
without subheadings.
It should be easily understood without reference to the text.
Running head and abbreviations. Include
an abbreviated title
(45 characters or less) and a list of definitions of any abbreviations
used in the manuscript. Because this is a
multidisciplinary journal,
abbreviations should be kept to a minimum. It is preferable to use
only universally understood abbreviations.
Only standard chemical
or nonproprietary pharmaceutical nomenclature should be
used. All abbreviations must be defined separately in
the title,
abstract, and text of the manuscript.
Introduction. This should be organized and expressed in a way
that will introduce
and orient the general scientific reader to the
topic.
Methods. The Methods section should include a description of
the statistical
methods used.
Results. These may be presented in tables or figures that should
not duplicate the text. All tables and figures
must be numbered in
the order of their mention in the text.
Tables should be typed double-spaced as separate documents
from the text
of the manuscript. Do not use ditto marks. Center the
table number at the top of the page and the title of the table
beneath it.
A
reasonable number of black-and-white illustrations are permitted
without extra charge to the author. Figures must be of suitable
quality
for publication. Resolution for halftone images should be
300 dots per inch (dpi) at the size it will appear in print. Resolution
for
line art should be 1200 dpi at the size it will appear in
print. All images should be at least 5 inches wide. Preferably,
format for
digital files should be TIFF (Tagged image file format).
Images submitted in software-specific proprietary
formats (e.g., PowerPoint,
Harvard Graphics, Visio, etc.) must
meet specific conditions. Instructions for preparing artwork
for online submission can be found at
www.ees.elsevier.com/transres.
Consistency in size of illustrations
within the article is strongly
preferred. Any special instructions regarding sizing should be
clearly noted. Arrangements for the use
of figures requiring special
handling may be made with the Editor at an additional charge.
Legends for figures should be typed double-spaced
on a separate
page after the References.
Avoid duplicating previously published material. If it is necessary
to use a copyrighted
table, figure, or data, the figure legend or
table footnote should give full credit to the original source and
should state that the
material is reprinted with permission.
Discussion. The discussion should set the results in context and
set forth the major
conclusions of the authors. Information from
the Introduction or Results section should not be repeated unless
necessary for clarity.
The authors' speculations concerning the
possible implications of the findings may be presented in this
section but should be clearly
separated from the direct inferences.
As the Journal and its audience are multidisciplinary, we encourage
the inclusion of a short concluding
paragraph, under the
subheading "Speculations," which would point out and clearly
denote such broader possibilities for the general readership.
Acknowledgment(s)
In addition to the customary recognition of nonauthors who have
been helpful to the work described, this
section must disclose where appropriate all sources of support for the investigation, any
substantive conflicts of interest and clinical
trial registry information.
References. All references must be cited in the text. These should
be numbered serially in the
text and listed, in the order cited, after
any personal acknowledgments. Reference format should follow
the style outlined in Uniform
Requirements for Manuscripts
Submitted to Biomedical Journals (Vancouver style). Journal
abbreviations should conform to the style
of the Cumulated Index
Medicus. If not listed in the CIM, journal titles should not be
abbreviated. Authors are responsible for the accuracy
of their
references. Note: Unpublished results and personal communications
do not belong in the reference list; they should be cited
parenthetically in the text.
EXAMPLES (if six or fewer authors, list all; if seven or more, list
first three and add et al.):Journal
articles:
You CH, Lee KY, Chey WY, Menguy R. Electrogastrographic
study of patients with unexplained nausea, bloating and vomiting.
Gastroenterology 1999;79:311-4.
Books:
Langer M, Chiandussi L, Chopra IJ, Martini L, editors. The
endocrines and the
liver. London: Academic Press, 2004:9-34.
Chapters in books:
Gustafsson JA, Eneroth P, Hokfelt T, Mode A, Norstedt G.
Studies on the hypothalamo-pituitary axis: a novel concept in
regulation of steroid and drug metabolism. In: Langer M, Chiandussi
L,
Chapra IJ, Martini L, editors. The endocrines and the
liver. London: Academic Press, 2005:9-34.
Color Figures
Authors are
encouraged to submit color figures, which will be
published online at no cost; however, the expense of reproducing color
figures in print
must be borne by the authors. The charge for reproduction of
color figures is $650 for the first figure and $100 for each
subsequent figure.
Any figure submitted in color and requiring color for adequate representation
of data-as judged by the reviewers-will
be reviewed and processed with
the understanding that the figure will appear in color in the printed version of
the journal at the author's
expense. Authors unable to pay color figure
charges may request a waiver in the cover letter at the time of submission.
Permissions
and patient consent forms
Direct quotations, tables, or illustrations that have appeared in
copyrighted material must be accompanied
by written permission
for their use from the copyright owner and original author, along
with complete information as to source. Photographs
of identifiable
persons must be accompanied by signed releases showing
informed consent.
Authorship statement
At the time
of submission, the Journal requires an explicit statement by the senior corresponding author warranting that the manuscript, as submitted,
has been reviewed by and approved by all named authors; that the corresponding author is empowered by all of the authors to act on their
behalf with respect to the submission of the manuscript; that the article is original; that thearticle does not infringe upon any copyright
or other proprietary right of any third party; that neither the text nor the data reported have been published previously (abstracts
excepted); and that the article or a substantially similar article is not under consideration by another journal at this time. Include
this author agreement in the cover letter to be submitted online.
Patricia L. Hogan
Publisher, US Health Sciences Journals
Elsevier
360 Park Ave. South
New York, NY 10010
P.Hogan@elsevier.com
Updated September 2007
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